Evaluation of a disposable stirred tank bioreactor for cultivation of mammalian cells
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چکیده
منابع مشابه
Evaluation of a disposable stirred tank bioreactor for cultivation of mammalian cells
Introduction Disposable bioreactors are increasingly gaining acceptance for cell culture applications due to a number of advantages including ease of use and reduced labour costs, less requirements for utilities such as steam and purified water. In addition, the system requires no cleaning or cleaning validation and only a reduced clean room footprint. Integrated ready to use pre-sterilised dis...
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The influence of power consumption on the volumetric mass transfer coefficient was studied in a 5 liter stirred tank bioreactor during cultivation of a recombinant Chinese Hamster Ovary (CHO) cell line, which requires low aeration and mixing intensity. Under these conditions and at high cell concentrations, oxygen mass transfer coefficient and consequently volumetric oxygen mass transfer rate w...
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Introduction Influenza is one of the major viral diseases and has tremendous importance for human and animal health worldwide. The etiologic agent, Influenza A virus belongs to the family Orthomyxoviridae and is a single stranded (-) enveloped RNA virus with round shape and a diameter of 90-130 nm. Its genome consists of 8 segments which code for up to 11 proteins. The major surface proteins an...
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In the present study, commonly used weakly compressible lattice Boltzmann method and Guo incompressible lattice Boltzmann method have been used to simulate fluid flow in a stirred tank. For this purpose a 3D Parallel code has been developed in the framework of the lattice Boltzmann method. This program has been used for simulation of flow at different geometries such as 2D channel fluid flow an...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2011
ISSN: 1753-6561
DOI: 10.1186/1753-6561-5-s8-p54